But according to a group of researchers from the U.S., there is a chemical in the brain that become major cause itching.
In fact according to the researchers, in the absence of these compounds, there would be no itching or scratching his desire for the body that feels itchy.
The team of researchers from the National Institutes of Health, Maryland tested a variety of chemical compounds that carry information to the brain to find out what's behind the emergence of compound itch.
Until finally they found a compound called Npbb.
"When we exposes Npbb deficient mice with a substance that can trigger itching and we were very impressed because nobody saw it happen. Mice were not scrape himself," said research team leader Santosh Mishra as reported by the Daily Mail, Friday (
24.05.2013).
Conversely, when the mice were given injections contains Npbb, they immediately started scratching his body.
According to the researchers, the findings could provide hope finding better treatments for people who suffer from a disease that makes the skin feel very itchy.
Among people with eczema, diabetes and liver disorders.
Similarly, kidney dialysis patients who often suffer from severe itching, or cancer patients who often faced with the reality that pain relievers cause severe irritation on their skin until they are forced to stop treatment.
Moreover, the skin damage caused by constant scratching activity can cause infections in patients who are terminally ill.
Even so, the researchers emphasize that the finding of Npbb which also has other important roles in the body, the solution does not merely create a drug that can inhibit the performance of the compound.
"The challenge is to find a similar biosirkuit on people, evaluate and identify what molecules can be targeted for lethal chronic itching without causing unwanted side effects. So this is just the beginning," said another researcher, Dr. Mark Hoon.
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